Sunday, September 14, 2014

Physiology of Elephantiasis

Elephantiasis, X-ray
The picture above shows an x-ray highlighting
the lymph system with elephantiasis.

Elephantiasis directly affects the lymphatic system and will eventually disrupt the integumentary system. The lymphatic system which is a subset of the circulatory system regulate the bodies fluids. The lymph system has a net work of lymph vessels and has an immune response which uses antibodies to attacks diseases. The integumentary system is what protects the inside of the body it consists of skin, hair, nails, and exocrine glands.
The filariae nematode worm cause an obstruction of the lymphatic vessels. (I will discuss what exactly what filariea is and how it's acquire in a future blog post.) Once the filariae invade the lymph vessels they mature and cause blockages in the lymphatic system; mostly by or in reproductive organs and the urinary system. The blockages become worse over time and lead to hyperplasia (an increase in cell production) of the connective tissues in the lowest layer of the dermis causing large masses to form. "The secondary and recurrent bacterial or fungal infections act to form the rough appearance of limbs and other parts of the body like elephant hide" (Tada).






References  
Tada, Isao. "Pathogenesis and Treatment of Chronic Symptoms with Emphasis on Chyluria and Elephantiasis." March 2011. Trop Med Health.

http://www.factmonster.com/ipka/A0774536.html
http://www.sciencephoto.com/media/257042/view(Picture)

3 comments:

  1. So are there any treatments for elephantitis, or is surgery the only option to alleviate this disorder? And if there are treatments what is the success rate of the treatment?

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    1. Yes, there is treatments for elephantiasis. The medicine that is administered can only kill the parasitic worm and does not bring the infected areas back to normal size; if it's possible, the enlarged body masses can be surgically removed. There is an almost 100% success rate for treatment of killing the parasitic worms.

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  2. I'm ready to read about how these worms are acquired into the body. I wonder if it is based on environment, living conditions, or by ingestion of certain foods. It's kinda crazy that one worm can cause such huge problems!

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